Planning a BioMedCEP project proposal

Events, complex events, complex event processing

We keep it intentionally open as long as ...

Postby rainer93138 » Thu Nov 24, 2011 5:57 am

We keep it intentionally open as long as we have not completed the consortium formation.

Minutes from concal 21 Nov 2011:

0) The next concal
will take place in 2 weeks, same time. All of the attendees would accept this date of 5 Dec 2011, 4-6 pm. I'll send you the invitation within the next days.

1) Papers
All potential authors as listed in the papers have confirmed to write the full papers, even as more elaborated version of around 20 pages.
We are already discussing with some of our colleagues in this round, how we should publish these papers, ideas welcome.
The teams of the papers should team up themselves ASAP and come with an outline to the next concal, so we could decide who would contribute what to a paper and in which extent, perhaps similar to the first extended abstract http://www.citt-online.de/downloads/3-D ... Etzion.pdf.

2) ToDos
We discussed the overview doc of open and future calls. Nobody has additional suggestions for opportunities so far.
Everybody will send - within the next 2 weeks - his/her opinion of
2.1) which workprogramme and which topic(s) we should join
2.2) as IP and/or STREP

3) Potential coordinator
- must be decided until submission for pre-check.
- should be a well known organisation/person in the field(s) of BioMedCEP
- with a history and good experience of contributing to EC work programmes and working with EC units
- should know the head(s) of units personally and could call/contact them directly
- should know the internal Brussels EC procedures and routines, preassessment situation, hearing...
- ideally should have been a member of an Advisory Group of a work programme or a Topic/Challenge

3.1) Scientific and financial management: may be one or separate roles
3.2) (industrial) Big Dog needed? as coordinator (Andrea Gaggioli suggested Siemens)? (see FAQ's of EC websites, seems it's not a MUST anymore to include Big Dogs at all, we discussed the problems of Big Dogs with patents and with contributing to EU projects at all, etc., see also our discussion in the past viewtopic.php?f=13&t=295)
3.3) Experienced university (necessary as coordinator in the case of an IP?)
3.4) Most topics must be SME led (as you can see from my doc of open and future calls), SME must not, but can take the coordinator role and this would then be an extra-plus. EC has changed policies to strengthen the role and motivation of innovative SME's, as it seems - at least at some of the units/topics.
Must be discussed with the EC unit which we would like to select for the proposal.

4) Presentation of ideas at the next concal
Andreas Schuppert (RWTH Aachen) will give a presentation of the idea "Disease modelling, bio-markers and virtual physiology ..." and will send an outline.

5) Japan Shonan BioMedCEP seminar
Because I got mail from colleague who would like to join, problems are:
- We would have a strong subject for such a seminar with BioMedCEP. But we would have to motivate around 20 or more people.
- Deadline for the submission is already 15 Dec 2011. The enthusiasm was not so big on Monday;-) or it came too suddenly of course.
But we should keep it in our minds, perhaps we submit the same idea some months later.
------------------------------------------------------

- We'll summarize all your ideas before the next concal, so everybody can attend concretely prepared.

-----------------------------------------------------
Please send your ideas, elaboration and your special "customization" of a draft skeleton of a workpackages structure (see below), in order to get a "feeling" how it could look like and who could contribute to which work package. And perhaps we can already discuss the criteria how to write a good proposal http://cordis.europa.eu/fp7/ict/fet-pro ... -04_en.pdf (although this is not a guarantee, as the most of you know;-))

Draft skeleton of a workpackages structure

Titel: -tbd -
Acronym: BioMedCEP

Abstract:
-tbd -

WP1: Management

WP2: Definition of a BioMedCEP reference model and reference architecture
2.1 Brain Computer Interfaces - from and to the brain
2.1.1 from the brain
2.1.2 to the brain
2.2 Wearable Technologies, Body Area Networks
2.3 Bio-sensors, Event Adapters, communication approaches for living cells
2.4 Exocortex approaches, event processing, mapping complex events to the brain, U-CEP engines
2.5 Enhancing sensitivity ranges of humans
2.6 Adding additional senses to humans
...

WP3: Modelling notations and execution languages
3.1 Evaluation of existing modelling notations and standards
3.2 Evaluation of existing execution languages
3.3 Standardizing of modelling notations and execution languages
3.4 Domain-specific reference models and architectures for event patterns (as NEAx)
...

WP4: Definition of bio-sensors and bio-markers for diseases, definition of treatments/processes regarding influencing the protein machinery and the metabolism
4.1 Depression or burn out
4.2 Diabetes
4.3 Obesity
4.4 Ageing, longevity, quality of life...
...

WP5: Implementation and installation of Labs, Exploitation
5.1 BrainPort and CN-NINM
5.2 Wearable Technologies, Body Area Networks
5.3 Bio-seonsors, Event Adapters, communication approaches for living cells
5.4 Exocortex approaches, event processing, mapping complex events to the brain, U-CEP engines
5.5 Enhancing sensitivity ranges of humans
5.6 Adding additional senses to humans
...

WP...

WPx: Dissemination
x.1
...

Image
Download as ppt: http://www.citt-online.com/downloads/WP ... eleton.ppt
Feel free to change and send back to
rainer.ammon@citt-online.com
Last edited by rainer93138 on Fri Dec 16, 2011 2:14 am, edited 2 times in total.
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Re: Planning a BioMedCEP project proposal

Postby rainer93138 » Thu Nov 24, 2011 6:41 am

...In my opinion, the most adapted call is the EU FET Call 9 NBIS, though the EU FET Call 9 FOCAS could also be thought of. An IP is possible only if we find a good coordinator. As I don't know most of you, I have no idea who would accept this role.

In the program, I would add a Section devoted to Aging problems and the use of sensors to have a better prevention/immediate treatment of old people, allowing for an increased quality of life, if possible at home.

Hoping we'll propose a good project
Andree

Andree Ehresmann, U Picardie
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Re: Planning a BioMedCEP project proposal

Postby rainer93138 » Thu Nov 24, 2011 7:03 am

>> In the program, I would add a Section devoted to Aging problems and the use of sensors to have a better
>> prevention/immediate treatment of old people, allowing for an increased quality of life, if possible at home.

I fully support this idea

Andrea Gaggioli
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Re: Planning a BioMedCEP project proposal

Postby rainer93138 » Thu Nov 24, 2011 7:04 am

I fully agree with the proposition of Andree. Ageing could be a perfect medical framework. It is high on the politcal agenda for rising healthcare costs and expected lack of labour force to sustain healthcare in the near future.
Issues like comorbidity and complex interactions with the environment make that current approaches to understand causal relations to reach targeted treatment will probably fail.
A nice challenge for the VPH community!

Regards
Carel

Dr. C.G.M. Meskers MD PhD
Consultant in Physical Medicine and Rehabilitation, Associate Professor
Department of Rehabilitation Medicine, B0-Q
Leiden University Medical Center
P.O. Box 9600
2300 RC Leiden, The Netherlands
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Re: Planning a BioMedCEP project proposal

Postby rainer93138 » Thu Nov 24, 2011 7:04 am

I also agree with initiatives aiming to unravel mechanisms underlying aging and how diseases affect the aging process. It is of great interest to relate environmental, mental and cognitive aspects/events to mobility as a key factor in healthy aging, in particular the state of the neuromuscular system.

Regards,

Erwin de Vlugt, PhD
Assistant Professor
Neuromuscular Control Laboratory
Biomechanical Engineering
Delft University of Technology
The Netherlands
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Re: Planning a BioMedCEP project proposal

Postby rainer93138 » Thu Nov 24, 2011 7:15 am

Thanks Andree.

Ad work programme / challenge / topic:
I agree: EU FET Call 9 NBIS, though the EU FET Call 9 FOCAS would fit
but in the case of FET proposal it must be a radical new approach/breakthrough, which does not fit to another challenge/topic. We must check this in advance or shape the proposal accordingly.

Ad coordinator role in case of IP:
I'm in contact with my homecity and its BioPark
http://bioregio-regensburg.de/
I was teaching at Regensburg as adjunct professor in the last 20 years and there are good connections between some university institutes from Biology, Medieninformatik, Universitätsklinik, Medizin Informatik at U of Appl. Sc.

If our idea is more concrete, we shall find a solution.

Ad Aging problems and the use of sensors to have a better prevention/immediate treatment of old people, allowing for an increased quality of life, if possible at home
I suggest to add a package to

WP3: Definition of bio-sensors and bio-markers for diseases, definition of teatments/processes regarding influencing the protein machinery and the metabolism
3.1 Depression or burn out
3.2 Diabetes
3.3 Obesity
3.4 Ageing, longevity, quality of life... (have done in the meantime)
...
WP3 will be a vertical WP, some of the other WP's are horizontal. We'll draw a diagram of the WP-structure within the next days already. (have done in the meantime)
@Andree: please add your ideas to other WP's as well, according to what you or some of the colleagues would like to do with "Ageing..."

Again: we must check that such topics are not covered by other topics of the work programmes (see doc overview of open and future calls (from the previous posting).

@all: If not yet read, you find Andree's mathematical Ageing/U-CEP approach at
http://www.citt-online.de/downloads/EV-Poznan2011.pdf
or from 2010 workshop:
http://www.citt-online.com/downloads/Do ... M-UCEP.pdf
http://www.citt-online.com/index.php?id ... 0&id4=more
is published at Springer in the meantime
http://www.springer.com/computer/swe/bo ... 42-22759-2

BR
-rainer
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Re: Planning a BioMedCEP project proposal

Postby rainer93138 » Sat Nov 26, 2011 2:17 am

... Sure, I am open for collaboration in proposal…
BTW – put Kurt name in the author list, please

And our address is - TCNL, room M1012, 1550 University Ave, Biomedical Engineering Department, UW-Madison –

Yuri P. Danilov
Senior Scientist, Ph.D.
Biomedical Engineering Department
University of Wisconsin-Madison
Madison, Wisconsin, USA, 53706
Web: http://tcnl.bme.wisc.edu/home.php
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Re: Planning a BioMedCEP project proposal

Postby rainer93138 » Mon Nov 28, 2011 1:49 am

Remarks about fit with NBIS or FOCAS

So far, 2 opportunities of call 9 , FET Proactive are addressed (by Andree Ehresmann), the first is NBIS, the second is FOCAS:

http://cordis.europa.eu/fp7/ict/fet-pro ... ls_en.html

http://cordis.europa.eu/fp7/ict/fet-pro ... is_en.html

As I told at the last concal and as the most of you surely know, we must first check, whether it would be a waste of time and effort to submit a proposal.

We must check who of our potential consortium members had contributed to what in which role and what is his/her recommendation:

Last NBIS expert workshop 2009, shaping the IP
see expert list as well (there are some of our organisations listed, do you know the persons?):
ftp://ftp.cordis.europa.eu/pub/fp7/ict/ ... -04_en.pdf
see also ch. 5, flagship initiative "Multi Purpose Neuro Computer"
and compare the 6 flagship SA projects (see Wolfgang Boch slides http://cordis.europa.eu/fp7/ict/fet-pro ... -07_en.pdf), which were started 2011; 2 of them should be started as flagships 2013 for 10 years (FET-F 2020 and Beyond programme)

NBIS proposers day 2011, May, Budapest
There the budget, goals, outcomes, etc. were presented:
http://ec.europa.eu/information_society ... c_id=17796
Budget 23 Mio €, could mean:
- 1or 2 IPs (< 10 Mio),
- 1or 2 STREPs (< 2,5 Mio),
- 1 CSA (1 Mio) (exchanges, conferences, workshops, roadmapping, long-term cooperations)
--> USA U Wisconsin/TCNL
--> Japan NII Shonan (ditto)
--> CITT/BioPark/U or U ApplSc Regensburg
--> ??? who else would be interested ???
--> http://www.csnetwork.eu/ (to be commented by Andrea Gaggioli as member?)
--> Human Computer Confluence - HC squared /ditto Andrea Gaggioli)

1 IP perhaps points to Blue Brain and BrainScaleS (though U Heidelberg is already financed, 2011-2014, 8,5 Mio)? We should ask
- BrainScaleS viewtopic.php?f=13&t=285
perhaps look a nice presentation of BrainScaleS of Karl-Heinz Meier and his colleagues
https://brainscales.kip.uni-heidelberg. ... index.html
As it is obvious, BioMedCEP would thematically not compete but perfectly cooperate or use the
BrainScaleS or BlueBrain activities
.
and/or
- ask Henry Markram and his general project manager Felix Schürmann to avoid potential, senseless competition
(http://bluebrain.epfl.ch/page-58950-en.html, now called http://www.humanbrainproject.eu/index.html)

List of 12 proposers and their presentations
--> examples what could be submitted by whom
http://ec.europa.eu/information_society ... fm?id=5463

FOCAS does actually not fit regarding our aim, IMO
http://cordis.europa.eu/fp7/ict/fet-pro ... as_en.html

My 2 cents,

-rainer
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Re: Planning a BioMedCEP project proposal

Postby rainer93138 » Tue Nov 29, 2011 8:53 am

... NBIS seems really the 'good' call, and the workpackage well fit.
May I suggest to add

Strategies to cope with mental deficits, neuro-degenerative diseases and learning deficiencies.
More efficient methods in education. ...

Andree Ehresmann, U Picardie
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Re: Planning a BioMedCEP project proposal

Postby rainer93138 » Mon Dec 05, 2011 5:41 am

...
In answer to your call for input for the BioMedCEP project proposal we hereby want to outline the way the Delft (Delft University of Technology) and Leiden (Leiden University Medical Center) contribution might look like.

Delft is strong on bio- and neuromechanical modeling and control; Leiden is strong on clinical implication: diabetes, elderly with multimorbidity and stroke patients.

As far as we understand, the main issue is about brain computer interfacing and interaction with the environment. It is not quite clear to us what on what level input-output relations are defined: on cell- organ or organism level? We would like to define human interaction with the environment in terms of mobility, which is a definable entity and is clinically very relevant, e.g. sarcopenia in elderly and obesitas.

We may consider mobility, i.e. human movement in daily life and under ecological conditions (can be measured with e.g. accelerometers) as the parameter of environmental interaction and the human brain as the initiator and controller of movement.

Then there is one layer in between the controller (the brain) and the environmental interaction (movement) and that are the biomechanical constraints that may put a limit or filter on the brain output and vice versa, puts a limit on the input to the brain.

In order to understand the potential added value of brain augmenters it is then of vital importance to understand the characteristics of the neuromechanical filter.

The input of the Delft- Leiden group may therefore be on the assessment of the neuromechanical filter characteristics under healthy conditions and in a wide range of pathology.

We are excited about the possibilities of the BioMedCEP initiative and are looking forward to take part in further discussions.

Best regards

Carel Meskers
Erwin de Vlugt

Dr. C.G.M. Meskers MD PhD
Consultant in Physical Medicine and Rehabilitation, Associate Professor
Department of Rehabilitation Medicine, B0-Q
Leiden University Medical Center
P.O. Box 9600
2300 RC Leiden, The Netherlands
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